Chris A. Garces, M.D.

 

PUBLICATIONS:

1. Garces, CA: Kurenova, EV: Golubovskaya, VM: Cance, WG: Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3) and Focal Adhesion Kinase (FAK) Bind and Suppress Apoptosis in Breast Cancer Cells. Cancer Research. 2006; 66(3): 1446-54.

2.  Berry, SE; Garces, C; Hwang, HS; Kunugi, K; Meyers, M; Davis, TW; Boothman, DA; Kinsella, TJ: The Mismatch Repair Protein, hMLH1, Mediates 5-substituted Halogenated Thymidine Analogue Cytotoxicity, DNA Incorporation, and Radiosensitization in Human Colon Cancer Cells. Cancer Research. 1999; 59(8): 1840-5.

3. Davis, TW; Wilson-Van Patten, C; Meyers, M; Kunugi, K; Cuthill, S; Reznikoff, C; Garces, C; Boland, C; Kinsella, TJ; Rishel, R; Boothman, D: Defective Expression of the DNA Mismatch Repair Protein, MLH1 Alters G2-M Cell Cycle Checkpoint Arrest Following Ionizing Radiation. Cancer Research. 1998; 58: 767-778.


ABSTRACTS:

1. Garces, CA: Kurenova, EV: Golubovskaya, VM: Cance, WG: Vascular endothelial growth factor receptor-3 (VEGFR-3) 12mer peptide disrupts binding of focal adhesion kinase to VEGFR-3 and causes apoptosis in breast cancer cells. The 2nd annual Florida Tech Transfer Conference. 4/19/2005.

2. Garces, CA: Kurenova, EV: Golubovskaya, VM: Cance, WG: A novel binding partner of focal adhesion kinase, vascular endothelial growth factor receptor-3 (VEGFR-3), was discovered by phage display. Proceedings of the American Association for Cancer Research. 2005; 46: 807.

3
. Garces, CA: Kurenova, EV: Golubovskaya, VM: Cance, WG: Proceedings of the American Association for Cancer Research. 2005.  Poster: Anaheim, California.

4. Garces, CA: Kurenova, EV: Golubovskaya, VM: Beierle, E: Cance, WG: Inhibition of Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3) Binding to Focal Adhesion Kinase (FAK) Causes Apoptosis in Human Breast Cancer Cells.  Annals of Surgical Oncology. 2005; S9.  Oral presentation: Atlanta, Georgia.

5. Garces, CA: Chang, J: Wilson, RI: Kurenova, EV: Golubovskaya, VM: Cance, WG: Focal Adhesion Kinase Inhibitory Peptides Induce Apoptosis in Human Breast Cancer Cells.  Annals of Surgical Oncology. 2004; S68.  Oral presentation: New York, New York.

6. Garces, CA; Chang, J; Wilson, RI; Kurenova, EV; Golubovskaya, VM; Cance, WG: Isolation of a 12 Amino-acid Peptide that Binds to C-terminus of Focal Adhesion Kinase and Induces Apoptosis in Breast Cancer Cells.  AACR-NCI-EORTC International Conference Molecular Targets and Cancer Therapeutics. 2003; 102.  Poster: Boston, Mass.

7. Davis, TW; Van Patten, C; Garces, C; Kunugi, KA; Kinsella, TJ; Boothman, DA: Lack of Mismatch Repair (MLH1) Does Not Affect X-ray Survival, But Does Lead to Alterations in G2/M Cell Cycle Arrest.  Proceedings of the American Association for Cancer Research. 1996; 37: 601.

ORAL PRESENTATIONS:


1. Plenary session at SSO's 58th Annual Cancer Symposium 2005.  "Inhibition of Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3) Binding to Focal Adhesion Kinase (FAK) Causes Apoptosis in Human Breast Cancer Cells."


2. Plenary session at SSO's 57th Annual Cancer Symposium 2004.  "Focal Adhesion Kinase Inhibitory Peptides Induce Apoptosis in Human Breast Cancer Cells."


3. Florida Surgical Society 2004 Annual Meeting.  "Focal Adhesion Kinase Inhibitory Peptides Induce Apoptosis in Human Breast Cancer Cells."  Key West, Florida.


4. The Florida Chapter of the ACS 2004 Annual Meeting."Focal Adhesion Kinase Inhibitory Peptides Induce Apoptosis in Human Breast Cancer Cells."  Amelia Island, Florida.


BOOK CHAPTERS:


1. Garces, CA; McAuliffe, PF; Hochwald, SN; Cance, WG: Neoadjuvant Chemotherapy. Current Problems in Surgery. 2006; Accepted for publication.


MANUSCRIPTS:


1. Garces, CA and WG Cance: Neoadjuvant Chemotherapy of Breast Cancer. The American Surgeon. 2004; 70(7): 565-569.

 


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