|
Frank Orlando, M.D.
|
|||
|
Frank Orlando, M.D. completed his undergraduate
studies at SUNY-Binghampton in 2000, where he was Phi Beta Kappa. He
completed his medical studies at SUNY-Upstate Medical Center where
as a medical student, he conducted research with Michael Meguid,
Professor of Surgery. In 2005, he initiated his general surgery
residency at the University of Florida College of Medicine,
Jacksonville campus. As a medical student and surgery house officer,
Dr. Orlando has participated in several research projects, involving
nutrition and oncogenesis. Dr. Orlando works with Kevin Brown, Ph.D.
Dr. Brown’s laboratory is focused on DNA damage which initiates a
series of signals that trigger responses such as activating cell
cycle checkpoints, malignant transformation and apoptosis. These
pathways are crucial in maintaining stability of the human genome
and limiting cancer development. One focus of the lab is studying
how the kinases ATM and ATR function in damage response and how the
mismatch repair system (MMR) impacts upon ATM/ATR-dependent
checkpoint and apoptosis signaling. Publication: Ahmed BH, Ahmed A, Tan D, Awad ZT, Al-Aali AY, Kilkenny J, Orlando FA, et al. Post-laparoscopic cholecystectomy pain: effects of intraperitoneal local anesthetics on pain control – a randomized prospective double-blinded placebo controlled trial. Am Surgeon 2008;74:201-208. In Press: 1. Orlando FA, Dongfeng T, Baltodano JD, et al. Aberrant crypt foci as precursors in colorectal cancer progression. J Surg Oncol 2008. 2. Hassid VJ, Alrawi SJ, Orlando FA, Awad ZT. Genetic and molecular abnormalities in cholangiocarconogenesis. World J Gastroenterol 2008. Oral Presentation: Ai L, Kim WJ, Dyer LM, Orlando F, Brown KD. High TG2 expression in breast tumor cell lines is a potential resistance biomarker to several chemotherapy drugs. 13th Annual Multidisciplinary Symposium on Breast Disease, The Ritz-Carlton, Amelia Island, FL, February 16, 2008. Second Place Award. Invited Review: Orlando FA, Dyer LM, Brown KD. Clinical implications of breast cancer characterization by microarray and epigenetic profiling. Breast J 2008. Grant Writing: Epigenetic Profiling of Breast Cancer in African-America Women Health Disparities Research N.I.H. Loan Repayment Program Submitted December 2007 |
|||
