Peter R. Nelson, MD

Assistant Professor
Vascular Surgery

phone: 352-376-1611x6470
fax: 352-271-4510

Awards and Professional Interests - Research/Clinical Interests
References - Biosketch
Awards and Professional Interests
  • Summa Cum Laude, Phi Beta Kappa, 1988
  • Thomas Harrison Carmichael/Emily Leonard Carmichael Prize Scholarship in Physiology, 1988
  • National Research Scholarship Award, 1988, 1994
  • Resident Teacher of the Year, 1998
  • NESVS R. Clement Darling, Jr. Clinical Research Award Recipient, 1999
  • Resident Teacher of the Year, 1999
  • H. Brownell Wheeler Resident Award, 1999
  • Lifeline Foundation Joan L. and Julius H. Jacobson Research Initiatives in Vascular Disease Conference, Resident Research Award Recipient, 2001

Research/Clinical Interests
  • Clinical Interest: Endovascular Repair of Aortic Aneurysms Percutaneous Intervention for Peripheral Arterial Occlusive Disease
  • Academic Interest: Surgical Education, Evolution of Vascular Surgical Training, Medical Student Surgical Interest Group and Mentor Program
  • Research Interest: Vascular Biology of Intimal Hyperplasia (with specific interest in SMC migration), Modification of Vascular Stent Design (surface landscape, pharmacologic adjuncts, etc.), Genomic/Proteomic Determinants of Lower Extremity Revascularization Failure
References
  1. Feezor, RF, Nelson PR, Lee, WA, Seeger, JM, Cendan J. Laparoscopic repair of a type II endoleak following endovascular AAA repair. In Press, J Surg Endosc, 2005.
  2. Singh MJ, Rohrer MJ, Nelson PR, Itani MS, Cutler BS. The benefit of complete venacavography prior to percutaneous inferior vena cava interruption. Submitted, J Vasc Surg, 2004.
  3. Hollenbeck ST, Nelson PR, Yamamura S, Faries PL, Liu B, Kent KC. Intracellular calcium transients are necessary for platelet derived growth factor but not extracellular matrix protein induced vascular smooth muscle cell migration. J Vasc Surg, 2004;40:351-58.
  4. Lo C, Li J, Morris M, Vasiliu C, Rohrer MJ, Singh MJ, Cutler BS, Nelson PR. Superior Performance of Thrombomodulin Coated Small Caliber ePTFE Grafts. (Abstract) Journal of Surgical Research, Vol. 114 (2), pp. 263-264, 2003.
  5. Li J, Singh MJ, Vasiliu C, Hendricks G, Cutler BS, Nelson PR. Recombinant human thrombomodulin inhibits arterial neointimal hyperplasia following balloon injury. J Vasc Surg, 2004;39:1074-83.
  6. Cote M, Martella MB, Ligetti R, Cutler, BS, Nelson PR. Management of Hyperlipidemia in Peripheral Vascular Disease. J Vasc Nursing, 2003; 21:63-7.
  7. Grassbaugh JA, Nelson PR, Rzucidlo EM, Schermerhorn ML, Fillinger MF, Powell RJ, Zwolak RM, Cronenwett JL, Walsh DB. Blinded comparison of preoperative duplex ultrasound and conventional arteriography for planning tibial level revascularization. J Vasc Surg, 2003; 37:1186-90.
  8. Nelson PR, Kent KC. Nuclear microinjection of DNA into human vascular smooth muscle cells. J Surg Res, 2002; 106:202-8.
  9. Li J, Singh MJ, Nelson PR, Hendricks G, Itani M, Rohrer MJ, Cutler BS. Immobilization of human thrombomodulin to expanded polytetrafluoroethylene. J Surg Res, 2002; 105:200-8.
  10. Proia RR, Nelson PR, Mulligan-Kehoe MJ, Wagner RJ, Kehas AJ, Powell RJ. The effect of endothelial cell overexpression of plasminogen activator inhibitor – 1 (PAI-1) on smooth muscle cell migration. J Vasc Surg 2002;36:164-71.
  11. Nelson PR, Powell RJ, Schermerhorn ML, Fillinger MF, Zwolak RM, Walsh DB, Cronenwett JL. Early results of external iliac artery stenting combined with common femoral artery endarterectomy. J Vasc Surg, 2002;35:1107-13.
  12. Nelson PR, McEnaney PM, Callahan LA, Arous EJ. Impact of the endovascular-assisted in situ saphenous vein bypass technique on hospital costs. Ann Vasc Surg 2001;15:653-60.
  13. Nelson PR, Powell RJ, Proia RR, Fillinger MF, Zwolak RM, Walsh DB, Cronenwett JL. Results of endovascular superficial femoral endarterectomy. J Vasc Surg, 2001;34:526-31.
  14. Proia RR, Walsh DB, Nelson PR, Powell RJ, Fillinger MF, Zwolak RW, Cronenwett JL. Early results of infragenicular revascularization based solely on duplex arteriography. J Vasc Surg, 2001;33:1165-70.
  15. Sturdivant AL, Labombard FE, Nelson PR, Fillinger MF, Zwolak RM. Ultrasound-Guided Compression Versus Ultrasound-Guided Percutaneous Thrombin Injection of Postcatheterization Pseudoaneurysm: Case Study. J Vasc Tech, 2001;25:105-8.
  16. Connors JL, Walsh DB, Nelson PR, Powell RJ, Fillinger MF, Zwolak RW, Cronenwett JL. Pedal branch artery (PBA) bypass: a viable limb salvage option. J Vasc Surg, 2000;32:1071-9.
  17. Nelson PR, Kehas AJ, Wagner RJ, Proia RR, Cronenwett JL, Powell RJ. Smooth muscle cells alter endothelial cell regulation of smooth muscle cell migration. Surgical Forum, 2000;51:375-7.
  18. Proia RR, Nelson PR, Mulligan-Kehoe MJ, Wagner RJ, Kehas AJ, Powell RJ. Endothelial cell overexpression of plasminogen activator inhibitor – 1 (PAI-1) inhibits smooth muscle cell migration. Surgical Forum, 2000;51:371-3.
  19. Nelson PR, Arous EJ. Endovascular in-situ bypass decreases morbidity and hospital stay following infrainguinal arterial reconstruction. J Endovasc Ther 2000; 7:309-14.
  20. Arous EJ, Nelson PR, Yood SM, Kelly JJ, Sandor A, Litwin DEM. Hand-assisted, laparoscopic aortobifemoral bypass. J Vasc Surg 2000;31:1142-8.
  21. Nelson PR, Yamamura S, Mureebe L, Itoh H, Kent KC. Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase. J Vasc Surg 1998;27(1):117-25.
  22. Itoh H, Nelson PR, Kaiura TL, Kent KC. Distinct signaling pathways mediate extracellular matrix protein versus PDGF induced smooth muscle cell migration. Surgical Forum 1998;49:311-3.
  23. Nelson PR, Yamamura S, Kent KC. Platelet-derived growth factor and extracellular matrix proteins provide a synergistic stimulus for human vascular smooth muscle cell migration. J Vasc Surg 1997;26(1):104-12.
  24. Itoh H, Nelson PR, Mureebe L, Horowitz A, Kent KC. The role of integrins in saphenous vein vascular smooth muscle cell migration. J Vasc Surg 1997;25(6):1061-9.
  25. Mureebe L, Nelson PR, Yamamura S, Kent KC. The role of pp60 c-src in vascular smooth muscle cell migration. Surgery 1997;122(2):138-44.
  26. Harrington EO, Löffler J, Nelson PR, Kent KC, Simons M, Ware JA. Enhancement of migration by protein kinase C? and inhibition of proliferation and cell cycle progression by protein kinase C? in capillary endothelial cells. J Biol Chem 1997;272(11):7390-7.
  27. Nelson PR, Yamamura S, Kent KC. Extracellular matrix proteins are potent agonists of smooth muscle migration. J Vasc Surg 1996;24(1): 25-33.
  28. Yamamura S, Nelson PR, Kent KC. The role of protein kinase C in attachment, spreading, and migration of human endothelial cells. J Surg Res 1996;63(1):349-54.
  29. Yamamura S, Nelson PR, Mureebe L, Kent KC. Proliferation and migration of vascular smooth muscle cells are mediated by distinct signaling pathways involving phospholipase C. Surgical Forum 1996;47:362-4.
  30. Jiang B, Yamamura S, Nelson PR, Mureebe L, Kent KC. Differential effects of platelet-derived growth factor isotypes on human smooth muscle cell proliferation and migration are mediated by distinct signaling pathways. Surgery 1996;120(2):427-32.
  31. Yamamura S, Nelson PR, Kent KC. The role of intracellular calcium in migration of human vascular smooth muscle cells. Surgical Forum 1995;46:386-8.

 
Biosketch
Education
1988BS, TUFTS UNIVERSITY, Medford, MA
1992MD, UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL, Worcester, MA
2007MS Clinical Investigation, UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE, Advanced Postgraduate Program in Clinical Investigation (APPCI)
 
Postdoctoral Training
1992-1999UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER COORDINATED SURGICAL RESIDENCY PROGRAM, Worcester, MA William C. Meyers, MD, Chairman Chief Surgical Resident, 1998 - 1999
1994-1996HARVARD-LONGWOOD VASCULAR SURGERY RESEARCH TRAINING PROGRAM Harvard Medical School, Boston, MA Frank W. LoGerfo, MD, Program Director
1999-2001DARTMOUTH-HITCHCOCK MEDICAL CENTER FELLOWSHIP IN VASCULAR SURGERY Lebanon, NH Jack L. Cronenwett, MD, Chief, Section of Vascular Surgery
 
Academic Appointments
2004-Assistant Professor of Surgery University of Florida College of Medicine Division of Vascular Surgery and Endovascular Therapy Shands HealthCare at the University of Florida Malcom Randall VA Medical Center Director, Endovascular Mini-fellowship Member, Surgery Education Executive Committee Faculty Advisor, UF COM Surgical Interest Group
2001-2004Assistant Professor of Surgery and Cell Biology University of Massachusetts Medical School

 

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